Fillers are designed to smoothen the wrinkles, augment lips and reshape facial contours. HA filler is a clear gel, composed of hyaluronic acid, a natural substance that is found throughout your body. As this acid is not of animal or human origin, there is no risk of allergic reaction and no pretesting is needed. The most common areas for filler treatment are the glabellar lines (frown lines), the nasolabial folds ( laugh lines), and the lips, to provide fullness and shape. Fillers can also be used in combination with anti-wrinkle injection in the management of Frown lines.